Anadrol, also
known by its pharmaceutical name Oxymetholone, is a synthetic anabolic steroid
originally developed in the 1960s to treat conditions like anaemia and severe
weight loss. It is one of the strongest oral steroids, known for its powerful
bulking effects, rapid strength gains, and noticeable increases in muscle
volume in a short time.
How Anadrol Works
Anadrol works by
Increasing red
blood cell production, which boosts oxygen delivery to muscles.
Enhancing
protein synthesis, helping muscle fibres grow bigger and stronger.
Promoting
nitrogen retention, key for muscle repair and growth.
Although it
does not convert directly into estrogen, Anadrol can still cause estrogen-like
side effects, possibly due to its effect on progesterone or estrogen receptors.
Step-by-Step Usage Guide
Step 1: Evaluate If Anadrol Is Right for You
Ask yourself
Are you at
least intermediate level in your training?
Have you
completed natural bulking phases and hit a plateau?
Do you
understand steroid basics and on-cycle support?
If you're a
beginner, Anadrol is not ideal as a first steroid. It’s extremely potent and
has a high side effect profile. Consider Testosterone-only cycles first.
Step 2: Choose Your Goal – Bulking Only
Anadrol is best
for bulking cycles. It's not recommended for cutting because
It causes water
retention.
It gives you a
bloated, puffy look.
It increases
appetite (not ideal when trying to stay in a caloric deficit).
If your goal is
to gain 10-15 lbs of muscle in 4–6 weeks, Anadrol can help.
Step 3: Plan Your Cycle Length and Dosage
Beginner Dose:
25–50 mg/day
Intermediate:
50–100 mg/day
Cycle Length:
4–6 weeks max
Why short cycles?
Anadrol is
hepatotoxic (toxic to the liver). Longer usage risks serious liver damage.
Split dose if over 50 mg
Due to its
short half-life (~8–10 hours), split the dose into morning + evening to
maintain stable blood levels.
Step 4: Stack Smart (Optional)
Anadrol is
often stacked with
Testosterone (E
or Cyp) – for maintaining testosterone levels.
Deca Durabolin
– for joint relief and lean mass.
Trenbolone –
for advanced users only, due to high toxicity.
Avoid stacking
it with other oral steroids, such as Dianabol or Superdrol, to prevent liver
overload.
Step 5: Protect Your Liver and Manage Estrogen
On-Cycle
Support
Liver Support
Milk Thistle
TUDCA (stronger
option)
NAC (N-acetyl
cysteine)
Estrogen Control
Anadrol does
not aromatise, but still causes estrogenic effects. You may need:
AI (Aromatase
Inhibitor) like Arimidex (Anastrozole) – use only if you get signs like
gynecomastia.
SERMs like
Nolvadex for gynecomastia flare-ups.
Don’t use AIs
as a precaution unless symptoms appear, as they may crash estrogen levels,
affecting gains and mood.
Step 6: Monitor for Side Effects
Common Side
Effects
Water retention
Gynecomastia
(man boobs)
High blood
pressure
Liver toxicity
Acne and oily
skin
Headaches
Appetite
increase
Aggression or
mood swings
What to Do
Monitor BP
weekly
Blood work
before, during, and after the cycle
Don’t exceed
the recommended dosage or duration
Step 7: Train and Eat for Results
Anadrol shines
when paired with a serious training program and high-calorie, high-protein
diet.
Training Tips
Focus on
compound lifts (squats, deadlifts, presses)
Push
progressive overload – Anadrol increases strength fast
Rest enough (it
helps with recovery)
Diet Tips
Aim for a
caloric surplus
At least
1.2–1.5g protein per pound of bodyweight
Keep hydrated
to reduce water retention and support the liver
Step 8: Post-Cycle Therapy (PCT)
Anadrol shuts
down natural testosterone production. You must run PCT to recover.
PCT Plan (Standard)
Start: 1–2 days
after last Anadrol dose
Duration: 4
weeks
Typical Protocol:
Nolvadex
(Tamoxifen):
40/40/20/20 mg per day
or
Clomid
(Clomiphene): 50/50/25/25
mg per day
If you stack
with Testosterone, start PCT based on ester clearance (e.g., 2 weeks after last
Test E shot).
Step 9: Time Off Between Cycles
General rule
Time off = Time
on + PCT
Example
If your Anadrol
cycle is 6 weeks + 4 weeks PCT = take at least 10 weeks off before the next
cycle.
This gives your
body and liver time to recover.
Step 10: Assess Results and Health
After PCT, do
Blood work: Check testosterone, liver enzymes
(AST/ALT), cholesterol.
Body
composition check: Were
the gains muscle or mostly water?
Side effect
check: Did anything
persist? Hair loss, BP issues, etc.
If gains were
good and health markers are clear, you can consider future cycles with
adjustments.
Final Tips for Anadrol Use
Avoid alcohol
while on-cycle – extra liver stress
Avoid
sugary/junky foods – worsens bloating and BP
Don’t use
Anadrol back-to-back in cycles – very liver harsh
Don’t rely on
it for every bulking cycle – your body adapts
Anadrol is a
highly potent bulking steroid, offering huge muscle and strength gains in a
short time. But it comes with serious side effects, especially on the liver,
blood pressure, and hormone levels. It is not for beginners or those with
health issues.
If used
responsibly with proper support, moderate dosage, and strict post-cycle
therapy, Anadrol can be a powerful tool in a bulking arsenal. Always prioritise
your health and recovery, and never substitute steroids for consistent training
and diet.
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