Recent research
suggests that MOTS-c helps regulate metabolism, supports mitochondrial
function, and protects cells from stress. In humans, exercise increases MOTS-c
levels, and in mice, it has shown potential to enhance physical performance and
affect muscle gene expression.
Is MOTS-c approved for medical use?
No, it is still
experimental. It’s being studied for potential use in treating aging and
obesity, but the FDA has not approved it. It also cannot be legally compounded
into medications by pharmacies.
Is MOTS-c banned in sports?
Yes, the World
Anti-Doping Agency (WADA) prohibits it at all times under the category of
Metabolic Modulators. It activates AMPK, which is linked to energy regulation.
Can athletes get a Therapeutic Use Exemption
(TUE)?
No, because
there’s no approved medical use for MOTS-c, athletes cannot get a TUE for it.
Is MOTS-c used in dietary supplements?
No, MOTS-c is
not a legal or recognized dietary ingredient, and it cannot be legally included
in supplements.
Is MOTS-c available online?
Yes, many
websites sell MOTS-c “for research purposes only.” These products are not
regulated, and buying them carries legal and safety risks. Just because it’s
available doesn’t mean it’s safe or legal to use.
Is MOTS-c safe to use?
Its safety is
unknown. There are no clinical trials to confirm how or when MOTS-c is safe.
Reported side effects from users include:
Heart
palpitations or rapid heartbeat
Injection site
irritation
Insomnia
Fever
Athletes should
be extremely wary of experimental peptides, including the prohibited peptide
MOTS-c, which can be found on many websites with the label “for research
purposes only.”
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